Fragile X-associated Tremor/Ataxia Syndrome (FXTAS)
FXTAS was discovered less than a decade ago in 2001, after clinicians and researchers had begun to notice a pattern of neurological symptoms occurring in older (primarily male) grandparents and parents of those who had the previously discovered conditions of Fragile X syndrome (FXS) and Fragile X-associated primary ovarian insufficiency (FXPOI). All three conditions result from changes in the "Fragile X" gene (scientific term: FMR1 gene). Together, they make up the family of genetic conditions known as Fragile X-associated Disorders.
This website is dedicated to conveying information about FXTAS to families, health professionals, and others who are affected in some way by the condition. The site has been developed and is maintained by The National Fragile X Foundation (NFXF), which also maintains a website (www.FragileX.org) that has information on all three conditions but is primarily focused on FXS. Look to the navigation buttons on this page to begin your journey of learning more about FXTAS, and please don’t hesitate to contact the NFXF for more information and assistance.
The National Fragile X Foundation has produced a basic informational brochure about FXTAS that is available for free by clicking here or by calling the NFXF office toll-free at 800-688-8765.